Seth. Goldberg, et.al., Maintenance of glomerular filtration barrier integrity requires laminin alpha5., Journal of the American Society of Nephrology : JASN, 2010, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/20150535

Seth. Goldberg, et.al., Maintenance of glomerular filtration barrier integrity requires laminin alpha5., Journal of the American Society of Nephrology : JASN, 2010, 21

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-LAMA5)1Jhm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431872
• Tg(Nphs1-FLPo)1Jhm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431870

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• tubulointerstitial nephritis_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011405I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh
• polycystic kidney_Lama5<tm3Jhm>/Lama5<tm3Jhm>
  http://metadb.riken.jp/0008528I129S1Sv129X1SvJC57BL6CBALama5tm3JhmLama5tm3JhmLama5tm3Jhm
• abnormal kidney morphology_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0002135I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh
• podocyte foot process effacement_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0008140I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh
• decreased circulating serum albumin level_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0005419I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh
• edema_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0001785I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh
• increased urine protein level_Lama5<tm3Jhm>/Lama5<tm3Jhm>
  http://metadb.riken.jp/0002962I129S1Sv129X1SvJC57BL6CBALama5tm3JhmLama5tm3JhmLama5tm3Jhm
• glomerulosclerosis_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0005264I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh
• postnatal lethality, incomplete penetrance_Lama5<tm2Jhm>/Lama5<tm2Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011086I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm2JhmTgNPHS2cre295Lbh0Lama5tm2JhmTgNPHS2cre295Lbh
• abnormal renal glomerulus basement membrane morphology_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011348I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh
• increased urine protein level_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0002962I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh
• hematuria_Lama5<tm3Jhm>/Lama5<tm3Jhm>
  http://metadb.riken.jp/0005161I129S1Sv129X1SvJC57BL6CBALama5tm3JhmLama5tm3JhmLama5tm3Jhm
• expanded mesangial matrix_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011353I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh
• hematuria_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0005161I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh
• premature death_Lama5<tm3Jhm>/Lama5<tm3Jhm>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJC57BL6CBALama5tm3JhmLama5tm3JhmLama5tm3Jhm
• increased renal glomerulus basement membrane thickness_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0011409I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh
• increased circulating cholesterol level_Lama5<tm2Jhm>/Lama5<tm1Jhm>,Tg(NPHS2-cre)295Lbh/0
  http://metadb.riken.jp/0005178I129S1Sv129X1SvJC57BL6CBASJLLama5tm2JhmLama5tm1JhmTgNPHS2cre295Lbh0Lama5tm1JhmLama5tm2JhmTgNPHS2cre295Lbh

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-LAMA5)1Jhm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431872
• Tg(Nphs1-FLPo)1Jhm
  http://metadb.riken.jp/db/mgi_rdf/MGI:5431870