increased liver weight_Pten<tm1Hwu>/Pten<tm1Hwu>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Alb1-cre)1Dlr/0

http://metadb.riken.jp/0002981I129S4SvJae129S6SvEvTacFVBNPtentm1HwuPtentm1HwuSmad4tm21CxdSmad4tm21CxdTgAlb1cre1Dlr0TgAlb1cre1DlrSmad4tm21CxdPtentm1Hwu

increased liver weight_Pten<tm1Hwu>/Pten<tm1Hwu>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Alb1-cre)1Dlr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• SMAD family member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:894293
• transgene insertion 1, Derek LeRoith
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176944

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<tm1Hwu>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Tg(Alb1-cre)1Dlr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb1-cre)1Dlr|Smad4<tm2.1Cxd>|Pten<tm1Hwu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased liver weight
  http://purl.obolibrary.org/obo/MP_0002981

文献

http://purl.org/net/cito/citesAsAuthority

• Xiaoling. Xu, et.al., Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice., The Journal of clinical investigation, 2006, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/16767220