increased liver weight_Stk3<tm1.1Rjo>/Stk3<tm1.1Rjo>,Stk4<tm1.1Rjo>/Stk4<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0002981I129S6SvEvTacC57BL6CD1DBASJLStk3tm11RjoStk3tm11RjoStk4tm11RjoStk4tm11RjoTgAlbcre21Mgn0Stk3tm11RjoStk4tm11RjoTgAlbcre21Mgn

increased liver weight_Stk3<tm1.1Rjo>/Stk3<tm1.1Rjo>,Stk4<tm1.1Rjo>/Stk4<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• serine/threonine kinase 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928487
• serine/threonine kinase 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1929004
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stk3<tm1.1Rjo>/Stk3<tm1.1Rjo>,Stk4<tm1.1Rjo>/Stk4<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stk3<tm1.1Rjo>|Stk4<tm1.1Rjo>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CD-1 * DBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased liver weight
  http://purl.obolibrary.org/obo/MP_0002981

文献

http://purl.org/net/cito/citesAsAuthority

• Li. Lu, et.al., Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20080689