Li. Lu, et.al., Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/20080689

Li. Lu, et.al., Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Stk3<tm1.1Rjo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430537
• Stk4<tm1.1Rjo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430536
• Sav1<tm1.1Rjo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430538

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased hepatocellular carcinoma incidence_Stk3<tm1.1Rjo>/Stk3<tm1.1Rjo>,Stk4<tm1.1Rjo>/Stk4<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003331I129S6SvEvTacC57BL6CD1DBASJLStk3tm11RjoStk3tm11RjoStk4tm11RjoStk4tm11RjoTgAlbcre21Mgn0Stk3tm11RjoStk4tm11RjoTgAlbcre21Mgn
• abnormal liver morphology_Stk3<tm1.1Rjo>/Stk3<tm1.1Rjo>,Stk4<tm1.1Rjo>/Stk4<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000598I129S6SvEvTacC57BL6CD1DBASJLStk3tm11RjoStk3tm11RjoStk4tm11RjoStk4tm11RjoTgAlbcre21Mgn0Stk3tm11RjoStk4tm11RjoTgAlbcre21Mgn
• abnormal hepatocyte morphology_Stk3<tm1.1Rjo>/Stk3<tm1.1Rjo>,Stk4<tm1.1Rjo>/Stk4<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000607I129S6SvEvTacC57BL6CD1DBASJLStk3tm11RjoStk3tm11RjoStk4tm11RjoStk4tm11RjoTgAlbcre21Mgn0Stk3tm11RjoStk4tm11RjoTgAlbcre21Mgn
• increased liver weight_Sav1<tm1.1Rjo>/Sav1<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002981I129S6SvEvTacC57BL6CD1DBASJLSav1tm11RjoSav1tm11RjoTgAlbcre21Mgn0TgAlbcre21MgnSav1tm11Rjo
• increased liver tumor incidence_Sav1<tm1.1Rjo>/Sav1<tm1.1Rjo>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008019I129S6SvEvTacC57BL6CBACD1SJLSav1tm11RjoSav1tm11RjoTgCAGcreEsr15Amc0Sav1tm11RjoTgCAGcreEsr15Amc
• increased liver tumor incidence_Sav1<tm1.1Rjo>/Sav1<tm1.1Rjo>,Tg(MMTV-cre)4Mam/0
  http://metadb.riken.jp/0008019I129S6SvEvTacC57BL6CD1FVBNSJLSav1tm11RjoSav1tm11RjoTgMMTVcre4Mam0TgMMTVcre4MamSav1tm11Rjo
• increased liver tumor incidence_Stk3<tm1.1Rjo>/Stk3<tm1.1Rjo>,Stk4<tm1.1Rjo>/Stk4<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0008019I129S6SvEvTacC57BL6CD1DBASJLStk3tm11RjoStk3tm11RjoStk4tm11RjoStk4tm11RjoTgAlbcre21Mgn0Stk3tm11RjoStk4tm11RjoTgAlbcre21Mgn
• increased hepatocyte apoptosis_Stk3<tm1.1Rjo>/Stk3<tm1.1Rjo>,Stk4<tm1.1Rjo>/Stk4<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003887I129S6SvEvTacC57BL6CD1DBASJLStk3tm11RjoStk3tm11RjoStk4tm11RjoStk4tm11RjoTgAlbcre21Mgn0Stk3tm11RjoStk4tm11RjoTgAlbcre21Mgn
• abnormal liver sinusoid morphology_Stk3<tm1.1Rjo>/Stk3<tm1.1Rjo>,Stk4<tm1.1Rjo>/Stk4<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0008989I129S6SvEvTacC57BL6CD1DBASJLStk3tm11RjoStk3tm11RjoStk4tm11RjoStk4tm11RjoTgAlbcre21Mgn0Stk3tm11RjoStk4tm11RjoTgAlbcre21Mgn
• increased hepatocellular carcinoma incidence_Sav1<tm1.1Rjo>/Sav1<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003331I129S6SvEvTacC57BL6CD1DBASJLSav1tm11RjoSav1tm11RjoTgAlbcre21Mgn0TgAlbcre21MgnSav1tm11Rjo
• increased carcinoma incidence_Sav1<tm1.1Rjo>/Sav1<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002038I129S6SvEvTacC57BL6CD1DBASJLSav1tm11RjoSav1tm11RjoTgAlbcre21Mgn0TgAlbcre21MgnSav1tm11Rjo
• increased hepatocyte proliferation_Sav1<tm1.1Rjo>/Sav1<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003893I129S6SvEvTacC57BL6CD1DBASJLSav1tm11RjoSav1tm11RjoTgAlbcre21Mgn0TgAlbcre21MgnSav1tm11Rjo
• increased hepatocyte proliferation_Stk3<tm1.1Rjo>/Stk3<tm1.1Rjo>,Stk4<tm1.1Rjo>/Stk4<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003893I129S6SvEvTacC57BL6CD1DBASJLStk3tm11RjoStk3tm11RjoStk4tm11RjoStk4tm11RjoTgAlbcre21Mgn0Stk3tm11RjoStk4tm11RjoTgAlbcre21Mgn
• increased liver weight_Stk3<tm1.1Rjo>/Stk3<tm1.1Rjo>,Stk4<tm1.1Rjo>/Stk4<tm1.1Rjo>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002981I129S6SvEvTacC57BL6CD1DBASJLStk3tm11RjoStk3tm11RjoStk4tm11RjoStk4tm11RjoTgAlbcre21Mgn0Stk3tm11RjoStk4tm11RjoTgAlbcre21Mgn

class

http://purl.org/net/cito/citesAsAuthority

• Stk3<tm1.1Rjo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430537
• Stk4<tm1.1Rjo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430536
• Sav1<tm1.1Rjo>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430538

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD16401
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16401
• CD28967
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD28967
• CD11791
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD11791
• CD16536
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16536