increased liver weight_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?

http://metadb.riken.jp/0002981I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn

increased liver weight_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• fatty acid synthase
  http://metadb.riken.jp/db/mgi_rdf/MGI:95485

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fasn<tm1Sem>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased liver weight
  http://purl.obolibrary.org/obo/MP_0002981

文献

http://purl.org/net/cito/citesAsAuthority

• Manu V. Chakravarthy, et.al., "New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis., Cell metabolism, 2005, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/16054078