Manu V. Chakravarthy, et.al., "New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis., Cell metabolism, 2005, 1

http://rdf.ncbi.nlm.nih.gov/pubmed/16054078

Manu V. Chakravarthy, et.al., "New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis., Cell metabolism, 2005, 1

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fasn<tm1.1Sem>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765071
• Fasn<tm1Sem>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765070

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating glucose level_Ppara<tm1Gonz>/Ppara<tm1Gonz>
  http://metadb.riken.jp/0005560I129S4SvJaePparatm1GonzPparatm1GonzPparatm1Gonz
• increased circulating free fatty acid level_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0001554I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• decreased circulating glucose level_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0005560I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• hepatic steatosis_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0002628I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• increased triglyceride level_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0005317I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• decreased saturated fatty acid level_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0005286I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• increased liver weight_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0002981I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• decreased circulating insulin level_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0002727I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• increased circulating cholesterol level_Ppara<tm1Gonz>/Ppara<tm1Gonz>
  http://metadb.riken.jp/0005178I129S4SvJaePparatm1GonzPparatm1GonzPparatm1Gonz
• decreased circulating cholesterol level_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0005179I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• increased circulating glucagon level_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0002712I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• increased circulating insulin level_Ppara<tm1Gonz>/Ppara<tm1Gonz>
  http://metadb.riken.jp/0002079I129S4SvJaePparatm1GonzPparatm1GonzPparatm1Gonz
• abnormal blood homeostasis_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0009642I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• increased circulating free fatty acid level_Ppara<tm1Gonz>/Ppara<tm1Gonz>
  http://metadb.riken.jp/0001554I129S4SvJaePparatm1GonzPparatm1GonzPparatm1Gonz
• decreased total body fat amount_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0010025I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• decreased total fat pad weight_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0008907I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn
• prenatal lethality, complete penetrance_Fasn<tm1.1Sem>/Fasn<tm1.1Sem>
  http://metadb.riken.jp/0011091I129X1SvJFVBNFasntm11SemFasntm11SemFasntm11Sem
• decreased liver cholesterol level_Fasn<tm1Sem>/Fasn<tm1Sem>,Tg(Alb-cre)21Mgn/?
  http://metadb.riken.jp/0010026I129X1SvJC57BL6DBAFasntm1SemFasntm1SemTgAlbcre21MgnFasntm1SemTgAlbcre21Mgn

class

http://purl.org/net/cito/citesAsAuthority

• Fasn<tm1.1Sem>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765071
• Fasn<tm1Sem>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765070