decreased mortality induced by ionizing radiation_Cdkn1a<tm1Hpw>/Cdkn1a<+>,Trp53<tm2Wahl>/Trp53<tm2Wahl>

http://metadb.riken.jp/0003010I129S4SvJae129X1SvJC57BL6Cdkn1atm1HpwCdkn1aTrp53tm2WahlTrp53tm2WahlCdkn1atm1HpwCdkn1aTrp53tm2Wahl

decreased mortality induced by ionizing radiation_Cdkn1a<tm1Hpw>/Cdkn1a<+>,Trp53<tm2Wahl>/Trp53<tm2Wahl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• cyclin-dependent kinase inhibitor 1A (P21)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104556

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn1a<tm1Hpw>/Cdkn1a<+>,Trp53<tm2Wahl>/Trp53<tm2Wahl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn1a<tm1Hpw>|Cdkn1a<+>|Trp53<tm2Wahl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased mortality induced by ionizing radiation
  http://purl.obolibrary.org/obo/MP_0003010

文献

http://purl.org/net/cito/citesAsAuthority

• Yunyuan V. Wang, et.al., Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity., Genes & development, 2011, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/21724834