abnormal long bone epiphyseal plate morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-GAL4)1Amc/0,Tg(Col2a1-PTHR1*H223R)AHju/?,Tg(UAS-IHH)1Amc/0

http://metadb.riken.jp/0003055I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1GAL41Amc0TgCol2a1PTHR1H223RAHjuTgUASIHH1Amc0TgUASIHH1AmcTgCol2a1GAL41AmcPthlhtm1HmkTgCol2a1PTHR1H223RAHju

abnormal long bone epiphyseal plate morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-GAL4)1Amc/0,Tg(Col2a1-PTHR1*H223R)AHju/?,Tg(UAS-IHH)1Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion A, Harald Juppner
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584002
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584008
• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584009
• parathyroid hormone-like peptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:97800

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-GAL4)1Amc/0,Tg(Col2a1-PTHR1*H223R)AHju/?,Tg(UAS-IHH)1Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(UAS-IHH)1Amc|Tg(Col2a1-GAL4)1Amc|Pthlh<tm1Hmk>|Tg(Col2a1-PTHR1*H223R)AHju

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal long bone epiphyseal plate morphology
  http://purl.obolibrary.org/obo/MP_0003055

文献

http://purl.org/net/cito/citesAsAuthority

• Tatsuya. Kobayashi, et.al., Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP., The Journal of clinical investigation, 2005, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/15951842