Tatsuya. Kobayashi, et.al., Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP., The Journal of clinical investigation, 2005, 115

http://rdf.ncbi.nlm.nih.gov/pubmed/15951842

Tatsuya. Kobayashi, et.al., Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP., The Journal of clinical investigation, 2005, 115

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ihh<tm2Amc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3526438

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal long bone hypertrophic chondrocyte zone_Ihh<tm2Amc>/Ihh<+>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Bglap2-cre)1Kry/0
  http://metadb.riken.jp/0000165I129S4SvJae129X1SvJC57BL6FVBNIhhtm2AmcIhhPth1rtm1HmkPth1rtm2HmkTgBglap2cre1Kry0Pth1rtm1HmkPth1rtm2HmkIhhIhhtm2AmcTgBglap2cre1Kry
• increased long bone epiphyseal plate size_Tg(Col2a1-GAL4)1Amc/0,Tg(UAS-IHH)1Amc/0
  http://metadb.riken.jp/0006398IC57BL6TgCol2a1GAL41Amc0TgUASIHH1Amc0TgUASIHH1AmcTgCol2a1GAL41Amc
• abnormal chondrocyte morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Bglap2-cre)1Kry/0,Tg(Col2a1-PTHLH)1Ecw/0
  http://metadb.riken.jp/0000166I129S2SvPas129S4SvJaeC57BL6FVBSJLPthlhtm1HmkPthlhtm1HmkPth1rtm1HmkPth1rtm2HmkTgBglap2cre1Kry0TgCol2a1PTHLH1Ecw0Pth1rtm1HmkPth1rtm2HmkTgCol2a1PTHLH1EcwTgBglap2cre1KryPthlhtm1Hmk
• long tibia_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Bglap2-cre)1Kry/0,Tg(Col2a1-PTHLH)1Ecw/0
  http://metadb.riken.jp/0004357I129S2SvPas129S4SvJaeC57BL6FVBSJLPthlhtm1HmkPthlhtm1HmkPth1rtm1HmkPth1rtm2HmkTgBglap2cre1Kry0TgCol2a1PTHLH1Ecw0Pth1rtm1HmkPth1rtm2HmkTgCol2a1PTHLH1EcwTgBglap2cre1KryPthlhtm1Hmk
• decreased long bone epiphyseal plate size_Pthlh<tm1Hmk>/Pthlh<+>
  http://metadb.riken.jp/0006396I129S2SvPasC57BL6Pthlhtm1HmkPthlhPthlhtm1HmkPthlh
• abnormal chondrocyte morphology_Ihh<tm2Amc>/Ihh<+>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Bglap2-cre)1Kry/0
  http://metadb.riken.jp/0000166I129S4SvJae129X1SvJC57BL6FVBNIhhtm2AmcIhhPth1rtm1HmkPth1rtm2HmkTgBglap2cre1Kry0Pth1rtm1HmkPth1rtm2HmkIhhIhhtm2AmcTgBglap2cre1Kry
• abnormal bone ossification_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Col2a1-PTHLH)1Ecw/0
  http://metadb.riken.jp/0008271I129S2SvPas129S4SvJaeC57BL6SJLPthlhtm1HmkPthlhtm1HmkPth1rtm1HmkPth1rtm2HmkTgCol2a1PTHLH1Ecw0Pth1rtm1HmkPth1rtm2HmkTgCol2a1PTHLH1EcwPthlhtm1Hmk
• abnormal long bone epiphyseal plate morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-GAL4)1Amc/0,Tg(Col2a1-PTHR1*H223R)AHju/?,Tg(UAS-IHH)1Amc/0
  http://metadb.riken.jp/0003055I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1GAL41Amc0TgCol2a1PTHR1H223RAHjuTgUASIHH1Amc0TgUASIHH1AmcTgCol2a1GAL41AmcPthlhtm1HmkTgCol2a1PTHR1H223RAHju
• abnormal facial morphology_Tg(Col2a1-GAL4)1Amc/0,Tg(UAS-IHH)1Amc/0
  http://metadb.riken.jp/0003743IC57BL6TgCol2a1GAL41Amc0TgUASIHH1Amc0TgUASIHH1AmcTgCol2a1GAL41Amc
• abnormal bone marrow development_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Col2a1-PTHLH)1Ecw/0
  http://metadb.riken.jp/0000168I129S2SvPas129S4SvJaeC57BL6SJLPthlhtm1HmkPthlhtm1HmkPth1rtm1HmkPth1rtm2HmkTgCol2a1PTHLH1Ecw0Pth1rtm1HmkPth1rtm2HmkTgCol2a1PTHLH1EcwPthlhtm1Hmk
• abnormal long bone hypertrophic chondrocyte zone_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/0
  http://metadb.riken.jp/0000165I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1PTHR1H223RAHju0Pthlhtm1HmkTgCol2a1PTHR1H223RAHju
• absent neurocranium_Tg(Col2a1-GAL4)1Amc/0,Tg(UAS-IHH)1Amc/0
  http://metadb.riken.jp/0000075IC57BL6TgCol2a1GAL41Amc0TgUASIHH1Amc0TgUASIHH1AmcTgCol2a1GAL41Amc
• decreased long bone epiphyseal plate size_Pthlh<tm1Hmk>/Pthlh<+>,Tg(Col2a1-GAL4)1Amc/0,Tg(UAS-IHH)1Amc/0
  http://metadb.riken.jp/0006396I129S2SvPasC57BL6Pthlhtm1HmkPthlhTgCol2a1GAL41Amc0TgUASIHH1Amc0Pthlhtm1HmkTgCol2a1GAL41AmcTgUASIHH1AmcPthlh
• short tibia_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Col2a1-PTHLH)1Ecw/0
  http://metadb.riken.jp/0002764I129S2SvPas129S4SvJaeC57BL6SJLPthlhtm1HmkPthlhtm1HmkPth1rtm1HmkPth1rtm2HmkTgCol2a1PTHLH1Ecw0Pth1rtm1HmkPth1rtm2HmkTgCol2a1PTHLH1EcwPthlhtm1Hmk
• decreased long bone epiphyseal plate size_Pthlh<tm1Hmk>/Pthlh<+>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Bglap2-cre)1Kry/0
  http://metadb.riken.jp/0006396I129S2SvPas129S4SvJaeC57BL6FVBNPthlhtm1HmkPthlhPth1rtm1HmkPth1rtm2HmkTgBglap2cre1Kry0Pth1rtm2HmkPthlhPth1rtm1HmkPthlhtm1HmkTgBglap2cre1Kry
• fused joints_Tg(Col2a1-GAL4)1Amc/0,Tg(UAS-IHH)1Amc/0
  http://metadb.riken.jp/0003189IC57BL6TgCol2a1GAL41Amc0TgUASIHH1Amc0TgUASIHH1AmcTgCol2a1GAL41Amc
• increased long bone epiphyseal plate size_Ihh<tm1Amc>/Ihh<+>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Bglap2-cre)1Kry/0
  http://metadb.riken.jp/0006398I129S1Sv129S4SvJae129X1SvJC57BL6FVBIhhtm1AmcIhhPth1rtm1HmkPth1rtm2HmkTgBglap2cre1Kry0Ihhtm1AmcPth1rtm1HmkPth1rtm2HmkIhhTgBglap2cre1Kry
• abnormal long bone epiphyseal plate morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Col2a1-PTHLH)1Ecw/0
  http://metadb.riken.jp/0003055I129S2SvPas129S4SvJaeC57BL6SJLPthlhtm1HmkPthlhtm1HmkPth1rtm1HmkPth1rtm2HmkTgCol2a1PTHLH1Ecw0Pth1rtm1HmkPth1rtm2HmkTgCol2a1PTHLH1EcwPthlhtm1Hmk
• decreased chondrocyte number_Tg(Col2a1-GAL4)1Amc/0,Tg(UAS-IHH)1Amc/0
  http://metadb.riken.jp/0000167IC57BL6TgCol2a1GAL41Amc0TgUASIHH1Amc0TgUASIHH1AmcTgCol2a1GAL41Amc
• increased long bone epiphyseal plate size_Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Bglap2-cre)1Kry/0
  http://metadb.riken.jp/0006398I129S4SvJaeC57BL6FVBPth1rtm1HmkPth1rtm2HmkTgBglap2cre1Kry0Pth1rtm2HmkPth1rtm1HmkTgBglap2cre1Kry
• abnormal long bone epiphyseal plate morphology_Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Bglap2-cre)1Kry/0
  http://metadb.riken.jp/0003055I129S4SvJaeC57BL6FVBPth1rtm1HmkPth1rtm2HmkTgBglap2cre1Kry0Pth1rtm2HmkPth1rtm1HmkTgBglap2cre1Kry
• abnormal chondrocyte morphology_Tg(Col2a1-GAL4)1Amc/0,Tg(UAS-IHH)1Amc/0
  http://metadb.riken.jp/0000166IC57BL6TgCol2a1GAL41Amc0TgUASIHH1Amc0TgUASIHH1AmcTgCol2a1GAL41Amc
• decreased long bone epiphyseal plate size_Ihh<tm1Amc>/Ihh<+>
  http://metadb.riken.jp/0006396I129S1Sv129X1SvJC57BL6Ihhtm1AmcIhhIhhIhhtm1Amc
• abnormal chondrocyte morphology_Ihh<tm1Amc>/Ihh<tm2Amc>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Bglap2-cre)1Kry/0
  http://metadb.riken.jp/0000166I129S1Sv129S4SvJae129X1SvJC57BL6FVBIhhtm1AmcIhhtm2AmcPth1rtm1HmkPth1rtm2HmkTgBglap2cre1Kry0Ihhtm2AmcTgBglap2cre1KryIhhtm1AmcPth1rtm1HmkPth1rtm2Hmk
• abnormal long bone epiphyseal plate morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Pth1r<tm1Hmk>/Pth1r<tm2Hmk>,Tg(Bglap2-cre)1Kry/0,Tg(Col2a1-PTHLH)1Ecw/0
  http://metadb.riken.jp/0003055I129S2SvPas129S4SvJaeC57BL6FVBSJLPthlhtm1HmkPthlhtm1HmkPth1rtm1HmkPth1rtm2HmkTgBglap2cre1Kry0TgCol2a1PTHLH1Ecw0Pth1rtm1HmkPth1rtm2HmkTgCol2a1PTHLH1EcwTgBglap2cre1KryPthlhtm1Hmk

class

http://purl.org/net/cito/citesAsAuthority

• Ihh<tm2Amc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3526438