abnormal long bone epiphyseal plate morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju

http://metadb.riken.jp/0003055I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuPthlhtm1Hmk

abnormal long bone epiphyseal plate morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• parathyroid hormone-like peptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:97800
• transgene insertion A, Harald Juppner
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584002

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Col2a1-PTHR1*H223R)AHju|Pthlh<tm1Hmk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal long bone epiphyseal plate morphology
  http://purl.obolibrary.org/obo/MP_0003055

文献

http://purl.org/net/cito/citesAsAuthority

• E. Schipani, et.al., Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9391087