E. Schipani, et.al., Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94

http://rdf.ncbi.nlm.nih.gov/pubmed/9391087

E. Schipani, et.al., Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide., Proceedings of the National Academy of Sciences of the United States of America, 1997, 94

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584013
• Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584015

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584013
• Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/db/mgi_rdf/MGI:3584015

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• short tail_Tg(Col2a1-PTHR1*H223R)BHju/Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/0000592IFVBNTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHju
• abnormal long bone epiphyseal plate morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/0003055I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuPthlhtm1Hmk
• delayed endochondral bone ossification_Tg(Col2a1-PTHR1*H223R)BHju/0
  http://metadb.riken.jp/0003419IFVBNTgCol2a1PTHR1H223RBHju0TgCol2a1PTHR1H223RBHju
• premature bone ossification_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>
  http://metadb.riken.jp/0003416I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkPthlhtm1Hmk
• delayed endochondral bone ossification_Tg(Col2a1-PTHR1*H223R)BHju/Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/0003419IFVBNTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHju
• increased diameter of tibia_Tg(Col2a1-PTHR1*H223R)BHju/Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/0008162IFVBNTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHju
• failure of tooth eruption_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/0000121I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuPthlhtm1Hmk
• delayed endochondral bone ossification_Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/0003419IC57BL6TgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHju
• abnormal vertebrae morphology_Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/0000137IC57BL6TgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHju
• abnormal bone mineralization_Tg(Col2a1-PTHR1*H223R)AHju/0
  http://metadb.riken.jp/0002896IC57BL6TgCol2a1PTHR1H223RAHju0TgCol2a1PTHR1H223RAHju
• abnormal long bone morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>
  http://metadb.riken.jp/0003723I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkPthlhtm1Hmk
• abnormal dentin morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/0002818I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuPthlhtm1Hmk
• abnormal vertebrae morphology_Tg(Col2a1-PTHR1*H223R)AHju/0
  http://metadb.riken.jp/0000137IC57BL6TgCol2a1PTHR1H223RAHju0TgCol2a1PTHR1H223RAHju
• domed cranium_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>
  http://metadb.riken.jp/0000440I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkPthlhtm1Hmk
• decreased length of long bones_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>
  http://metadb.riken.jp/0004686I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkPthlhtm1Hmk
• abnormal long bone metaphysis morphology_Tg(Col2a1-PTHR1*H223R)BHju/Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/0000133IFVBNTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHju
• abnormal vertebrae morphology_Tg(Col2a1-PTHR1*H223R)BHju/Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/0000137IFVBNTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHju
• abnormal tooth morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/0002100I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuPthlhtm1Hmk
• abnormal ameloblast morphology_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/0002650I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuPthlhtm1Hmk
• abnormal bone mineralization_Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/0002896IC57BL6TgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHju
• decreased long bone epiphyseal plate size_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>
  http://metadb.riken.jp/0006396I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkPthlhtm1Hmk
• short tibia_Tg(Col2a1-PTHR1*H223R)BHju/Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/0002764IFVBNTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHju
• short mandible_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>
  http://metadb.riken.jp/0000088I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkPthlhtm1Hmk
• abnormal hindlimb morphology_Tg(Col2a1-PTHR1*H223R)BHju/Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/0000556IFVBNTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHju
• abnormal bone ossification_Tg(Col2a1-PTHR1*H223R)BHju/Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/0008271IFVBNTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHju
• premature death_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/0
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1PTHR1H223RAHju0Pthlhtm1HmkTgCol2a1PTHR1H223RAHju
• short limbs_Tg(Col2a1-PTHR1*H223R)BHju/Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/0000547IFVBNTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHju
• premature death_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuPthlhtm1Hmk
• abnormal postnatal growth_Pthlh<tm1Hmk>/Pthlh<tm1Hmk>,Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju
  http://metadb.riken.jp/0001731I129S2SvPasC57BL6Pthlhtm1HmkPthlhtm1HmkTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuTgCol2a1PTHR1H223RAHjuPthlhtm1Hmk
• abnormal bone mineralization_Tg(Col2a1-PTHR1*H223R)BHju/Tg(Col2a1-PTHR1*H223R)BHju
  http://metadb.riken.jp/0002896IFVBNTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHjuTgCol2a1PTHR1H223RBHju
• delayed endochondral bone ossification_Tg(Col2a1-PTHR1*H223R)AHju/0
  http://metadb.riken.jp/0003419IC57BL6TgCol2a1PTHR1H223RAHju0TgCol2a1PTHR1H223RAHju