increased insulin secretion_Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0

http://metadb.riken.jp/0003058IC57BL6CBAAlox15tm11NadlAlox15tm11NadlTgPdx1cre891Dam0TgPdx1cre891DamAlox15tm11Nadl

increased insulin secretion_Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318
• arachidonate 15-lipoxygenase
  http://metadb.riken.jp/db/mgi_rdf/MGI:87997

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pdx1-cre)89.1Dam|Alox15<tm1.1Nadl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased insulin secretion
  http://purl.obolibrary.org/obo/MP_0003058

文献

http://purl.org/net/cito/citesAsAuthority

• Sarah A. Tersey, et.al., 12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets., Molecular and cellular biology, 2014, 34
  http://rdf.ncbi.nlm.nih.gov/pubmed/25071151