Sarah A. Tersey, et.al., 12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets., Molecular and cellular biology, 2014, 34

http://rdf.ncbi.nlm.nih.gov/pubmed/25071151

Sarah A. Tersey, et.al., 12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets., Molecular and cellular biology, 2014, 34

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Alox15<tm1.1Nadl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4889210

class

http://purl.org/net/cito/citesAsAuthority

• Alox15<tm1.1Nadl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4889210

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• pancreatic islet hyperplasia_Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005491IC57BL6CBAAlox15tm11NadlAlox15tm11NadlTgPdx1cre891Dam0TgPdx1cre891DamAlox15tm11Nadl
• abnormal enzyme/coenzyme level_Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005319IC57BL6CBAAlox15tm11NadlAlox15tm11NadlTgPdx1cre891Dam0TgPdx1cre891DamAlox15tm11Nadl
• improved glucose tolerance_Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0005292IC57BL6CBAAlox15tm11NadlAlox15tm11NadlTgPdx1cre891Dam0TgPdx1cre891DamAlox15tm11Nadl
• abnormal pancreas physiology_Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0002693IC57BL6CBAAlox15tm11NadlAlox15tm11NadlTgPdx1cre891Dam0TgPdx1cre891DamAlox15tm11Nadl
• abnormal pancreatic beta cell physiology_Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0003562IC57BL6CBAAlox15tm11NadlAlox15tm11NadlTgPdx1cre891Dam0TgPdx1cre891DamAlox15tm11Nadl
• decreased susceptibility to non-insulin-dependent diabetes_Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0020088IC57BL6CBAAlox15tm11NadlAlox15tm11NadlTgPdx1cre891Dam0TgPdx1cre891DamAlox15tm11Nadl
• increased insulin secretion_Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0003058IC57BL6CBAAlox15tm11NadlAlox15tm11NadlTgPdx1cre891Dam0TgPdx1cre891DamAlox15tm11Nadl
• abnormal redox activity_Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0003186IC57BL6CBAAlox15tm11NadlAlox15tm11NadlTgPdx1cre891Dam0TgPdx1cre891DamAlox15tm11Nadl
• increased pancreatic beta cell mass_Alox15<tm1.1Nadl>/Alox15<tm1.1Nadl>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009113IC57BL6CBAAlox15tm11NadlAlox15tm11NadlTgPdx1cre891Dam0TgPdx1cre891DamAlox15tm11Nadl