decreased insulin secretion_Arntl<tm2Bra>/Arntl<tm2Bra>,Tg(Pdx1-cre)89.1Dam/0

http://metadb.riken.jp/0003059I129C57BL6C57BL6JCBAICRArntltm2BraArntltm2BraTgPdx1cre891Dam0Arntltm2BraTgPdx1cre891Dam

decreased insulin secretion_Arntl<tm2Bra>/Arntl<tm2Bra>,Tg(Pdx1-cre)89.1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318
• aryl hydrocarbon receptor nuclear translocator-like
  http://metadb.riken.jp/db/mgi_rdf/MGI:1096381

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Arntl<tm2Bra>/Arntl<tm2Bra>,Tg(Pdx1-cre)89.1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Arntl<tm2Bra>|Tg(Pdx1-cre)89.1Dam

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * C57BL/6J * CBA * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased insulin secretion
  http://purl.obolibrary.org/obo/MP_0003059

文献

http://purl.org/net/cito/citesAsAuthority

• Biliana. Marcheva, et.al., Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes., Nature, 2010, 466
  http://rdf.ncbi.nlm.nih.gov/pubmed/20562852