decreased insulin secretion_Kif5b<tm1Njen>/Kif5b<+>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0003059I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5bTgIns2cre25Mgn0Kif5bKif5btm1NjenTgIns2cre25Mgn

decreased insulin secretion_Kif5b<tm1Njen>/Kif5b<+>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• kinesin family member 5B
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098268
• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kif5b<tm1Njen>/Kif5b<+>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kif5b<+>|Kif5b<tm1Njen>|Tg(Ins2-cre)25Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * C57BL/6N * DBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased insulin secretion
  http://purl.obolibrary.org/obo/MP_0003059

文献

http://purl.org/net/cito/citesAsAuthority

• Ju. Cui, et.al., Targeted inactivation of kinesin-1 in pancreatic β-cells in vivo leads to insulin secretory deficiency., Diabetes, 2011, 60
  http://rdf.ncbi.nlm.nih.gov/pubmed/20870970