Ju. Cui, et.al., Targeted inactivation of kinesin-1 in pancreatic β-cells in vivo leads to insulin secretory deficiency., Diabetes, 2011, 60

http://rdf.ncbi.nlm.nih.gov/pubmed/20870970

Ju. Cui, et.al., Targeted inactivation of kinesin-1 in pancreatic β-cells in vivo leads to insulin secretory deficiency., Diabetes, 2011, 60

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kif5b<tm1.1Njen>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810072
• Kif5b<tm1Njen>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3809821

class

http://purl.org/net/cito/citesAsAuthority

• Kif5b<tm1.1Njen>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810072
• Kif5b<tm1Njen>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3809821

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased insulin secretion_Kif5b<tm1Njen>/Kif5b<tm1.1Njen>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003059I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5btm11NjenTgIns2cre25Mgn0Kif5btm1NjenKif5btm11NjenTgIns2cre25Mgn
• decreased circulating insulin level_Kif5b<tm1Njen>/Kif5b<tm1.1Njen>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002727I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5btm11NjenTgIns2cre25Mgn0Kif5btm1NjenKif5btm11NjenTgIns2cre25Mgn
• increased pancreatic beta cell number_Kif5b<tm1Njen>/Kif5b<tm1.1Njen>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003645I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5btm11NjenTgIns2cre25Mgn0Kif5btm1NjenKif5btm11NjenTgIns2cre25Mgn
• abnormal pancreas physiology_Kif5b<tm1Njen>/Kif5b<tm1.1Njen>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002693I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5btm11NjenTgIns2cre25Mgn0Kif5btm1NjenKif5btm11NjenTgIns2cre25Mgn
• abnormal pancreatic beta cell physiology_Kif5b<tm1Njen>/Kif5b<tm1.1Njen>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003562I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5btm11NjenTgIns2cre25Mgn0Kif5btm1NjenKif5btm11NjenTgIns2cre25Mgn
• postnatal growth retardation_Kif5b<tm1Njen>/Kif5b<tm1.1Njen>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001732I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5btm11NjenTgIns2cre25Mgn0Kif5btm1NjenKif5btm11NjenTgIns2cre25Mgn
• decreased body weight_Kif5b<tm1Njen>/Kif5b<tm1.1Njen>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001262I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5btm11NjenTgIns2cre25Mgn0Kif5btm1NjenKif5btm11NjenTgIns2cre25Mgn
• small pancreatic islets_Kif5b<tm1Njen>/Kif5b<tm1.1Njen>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009172I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5btm11NjenTgIns2cre25Mgn0Kif5btm1NjenKif5btm11NjenTgIns2cre25Mgn
• impaired glucose tolerance_Kif5b<tm1Njen>/Kif5b<+>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5bTgIns2cre25Mgn0Kif5bKif5btm1NjenTgIns2cre25Mgn
• abnormal pancreatic beta cell morphology_Kif5b<tm1Njen>/Kif5b<tm1.1Njen>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005217I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5btm11NjenTgIns2cre25Mgn0Kif5btm1NjenKif5btm11NjenTgIns2cre25Mgn
• decreased insulin secretion_Kif5b<tm1Njen>/Kif5b<+>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003059I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5bTgIns2cre25Mgn0Kif5bKif5btm1NjenTgIns2cre25Mgn
• hyperglycemia_Kif5b<tm1Njen>/Kif5b<tm1.1Njen>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001559I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5btm11NjenTgIns2cre25Mgn0Kif5btm1NjenKif5btm11NjenTgIns2cre25Mgn
• impaired glucose tolerance_Kif5b<tm1Njen>/Kif5b<tm1.1Njen>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129S1SvC57BL6C57BL6NDBASJLKif5btm1NjenKif5btm11NjenTgIns2cre25Mgn0Kif5btm1NjenKif5btm11NjenTgIns2cre25Mgn