decreased insulin secretion_Pdx1<tm1Cvw>/Pdx1<+>,Pbx1<tm1Mlc>/Pbx1<+>

http://metadb.riken.jp/0003059I129S6SvEvTacC57BL6Pdx1tm1CvwPdx1Pbx1tm1MlcPbx1Pdx1Pbx1tm1MlcPdx1tm1CvwPbx1

decreased insulin secretion_Pdx1<tm1Cvw>/Pdx1<+>,Pbx1<tm1Mlc>/Pbx1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• pancreatic and duodenal homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:102851
• pre B cell leukemia homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97495

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdx1<tm1Cvw>/Pdx1<+>,Pbx1<tm1Mlc>/Pbx1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pdx1<+>|Pbx1<tm1Mlc>|Pdx1<tm1Cvw>|Pbx1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased insulin secretion
  http://purl.obolibrary.org/obo/MP_0003059

文献

http://purl.org/net/cito/citesAsAuthority

• Seung K. Kim, et.al., Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus., Nature genetics, 2002, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/11912494