decreased insulin secretion_Senp1<tm1.1Eyeh>/Senp1<tm1.1Eyeh>,Tg(Pdx1-cre/Esr1*)#Dam/0

http://metadb.riken.jp/0003059IC57BL6Senp1tm11EyehSenp1tm11EyehTgPdx1creEsr1Dam0Senp1tm11EyehTgPdx1creEsr1Dam

decreased insulin secretion_Senp1<tm1.1Eyeh>/Senp1<tm1.1Eyeh>,Tg(Pdx1-cre/Esr1*)#Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SUMO1/sentrin specific peptidase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2445054
• transgene insertion, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:5008262

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Senp1<tm1.1Eyeh>/Senp1<tm1.1Eyeh>,Tg(Pdx1-cre/Esr1*)#Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Senp1<tm1.1Eyeh>|Tg(Pdx1-cre/Esr1*)#Dam

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased insulin secretion
  http://purl.obolibrary.org/obo/MP_0003059

文献

http://purl.org/net/cito/citesAsAuthority

• Mourad. Ferdaoussi, et.al., Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells., The Journal of clinical investigation, 2015, 125
  http://rdf.ncbi.nlm.nih.gov/pubmed/26389676