increased susceptibility to ischemic brain injury_Braf<tm2Cpri>/Braf<+>,Tg(CMV-cre)1Cgn/0

http://metadb.riken.jp/0003076B6CgBraftm2CpriTgCMVcre1CgnBraftm2CpriBrafTgCMVcre1Cgn0Braftm2CpriTgCMVcre1CgnBraf

increased susceptibility to ischemic brain injury_Braf<tm2Cpri>/Braf<+>,Tg(CMV-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Braf transforming gene
  http://metadb.riken.jp/db/mgi_rdf/MGI:88190
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176179

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Braf<tm2Cpri>/Braf<+>,Tg(CMV-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Braf<tm2Cpri>|Tg(CMV-cre)1Cgn|Braf<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Braf<tm2Cpri> Tg(CMV-cre)1Cgn

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to ischemic brain injury
  http://purl.obolibrary.org/obo/MP_0003076

文献

http://purl.org/net/cito/citesAsAuthority

• Catherine. Andreadi, et.al., The intermediate-activity (L597V)BRAF mutant acts as an epistatic modifier of oncogenic RAS by enhancing signaling through the RAF/MEK/ERK pathway., Genes & development, 2012, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/22892241