abnormal cell nucleus morphology_Lmna<tm1.1Otin>/Lmna<+>

http://metadb.riken.jp/0003111I129P2OlaHsdC57BL6Lmnatm11OtinLmnaLmnatm11OtinLmna

abnormal cell nucleus morphology_Lmna<tm1.1Otin>/Lmna<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• lamin A
  http://metadb.riken.jp/db/mgi_rdf/MGI:96794

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lmna<tm1.1Otin>/Lmna<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lmna<tm1.1Otin>|Lmna<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cell nucleus morphology
  http://purl.obolibrary.org/obo/MP_0003111

文献

http://purl.org/net/cito/citesAsAuthority

• Isabel C. Lopez-Mejia, et.al., A conserved splicing mechanism of the LMNA gene controls premature aging., Human molecular genetics, 2011, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/21875900
• Fernando G. Osorio, et.al., Splicing-directed therapy in a new mouse model of human accelerated aging., Science translational medicine, 2011, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/22030750