increased erythroid progenitor cell number_Jak2<tm1(JAK2)Argr>/Jak2<+>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0003135I129S7SvEvBrdC57BL6CBAJak2tm1JAK2ArgrJak2TgMx1cre1Cgn0Jak2TgMx1cre1CgnJak2tm1JAK2Argr

increased erythroid progenitor cell number_Jak2<tm1(JAK2)Argr>/Jak2<+>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072
• Janus kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96629

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Jak2<tm1(JAK2)Argr>/Jak2<+>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Jak2<+>|Tg(Mx1-cre)1Cgn|Jak2<tm1(JAK2)Argr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased erythroid progenitor cell number
  http://purl.obolibrary.org/obo/MP_0003135

文献

http://purl.org/net/cito/citesAsAuthority

• Juan. Li, et.al., JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F-positive essential thrombocythemia., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20489053