decreased lysosomal enzyme secretion_Ctsk<tm1(cre)Ska>/Ctsk<+>,Plekhm1<tm1.1Hzhao>/Plekhm1<tm1.1Hzhao>

http://metadb.riken.jp/0003173IC57BL6JC57BL6NCrljCBAJNCrljCtsktm1creSkaCtskPlekhm1tm11HzhaoPlekhm1tm11HzhaoCtskCtsktm1creSkaPlekhm1tm11Hzhao

decreased lysosomal enzyme secretion_Ctsk<tm1(cre)Ska>/Ctsk<+>,Plekhm1<tm1.1Hzhao>/Plekhm1<tm1.1Hzhao>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• pleckstrin homology domain containing, family M (with RUN domain) member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2443207
• cathepsin K
  http://metadb.riken.jp/db/mgi_rdf/MGI:107823

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctsk<tm1(cre)Ska>/Ctsk<+>,Plekhm1<tm1.1Hzhao>/Plekhm1<tm1.1Hzhao>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctsk<+>|Ctsk<tm1(cre)Ska>|Plekhm1<tm1.1Hzhao>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased lysosomal enzyme secretion
  http://purl.obolibrary.org/obo/MP_0003173

文献

http://purl.org/net/cito/citesAsAuthority

• Toshifumi. Fujiwara, et.al., PLEKHM1/DEF8/RAB7 complex regulates lysosome positioning and bone homeostasis., JCI insight, 2016, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/27777970