thrombocytopenia_Hdac1<tm1Ics>/Hdac1<tm1Ics>,Hdac2<tm1.1Rdp>/Hdac2<+>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0003179I129S4SvJaeC57BL6CBAHdac1tm1IcsHdac1tm1IcsHdac2tm11RdpHdac2TgMx1cre1Cgn0Hdac2Hdac2tm11RdpHdac1tm1IcsTgMx1cre1Cgn

thrombocytopenia_Hdac1<tm1Ics>/Hdac1<tm1Ics>,Hdac2<tm1.1Rdp>/Hdac2<+>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• histone deacetylase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:108086
• histone deacetylase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097691
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hdac1<tm1Ics>/Hdac1<tm1Ics>,Hdac2<tm1.1Rdp>/Hdac2<+>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hdac2<+>|Hdac2<tm1.1Rdp>|Hdac1<tm1Ics>|Tg(Mx1-cre)1Cgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased platelet cell number
  http://purl.obolibrary.org/obo/MP_0003179

文献

http://purl.org/net/cito/citesAsAuthority

• Roel H. Wilting, et.al., Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis., The EMBO journal, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20571512