thrombocytopenia_Col1a1<tm6(tetO-MSI2)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0003179I129S4SvJaeC57BL6Col1a1tm6tetOMSI2JaeCol1a1GtROSA26Sortm1rtTAM2JaeGtROSA26SorGtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26SorCol1a1tm6tetOMSI2Jae

thrombocytopenia_Col1a1<tm6(tetO-MSI2)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm6(tetO-MSI2)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>|Col1a1<+>|Gt(ROSA)26Sor<+>|Col1a1<tm6(tetO-MSI2)Jae>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased platelet cell number
  http://purl.obolibrary.org/obo/MP_0003179

文献

http://purl.org/net/cito/citesAsAuthority

• Michael G. Kharas, et.al., Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia., Nature medicine, 2010, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/20616797