abnormal neuron apoptosis_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Jun<tm4Wag>/Jun<+>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0003202I129P2OlaHsdC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeJuntm4WagJunTgNescre1Kln0JunFbxw7tm11AxbeJuntm4WagTgNescre1Kln

abnormal neuron apoptosis_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Jun<tm4Wag>/Jun<+>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• jun proto-oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:96646
• F-box and WD-40 domain protein 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354695

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Jun<tm4Wag>/Jun<+>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Jun<+>|Fbxw7<tm1.1Axbe>|Jun<tm4Wag>|Tg(Nes-cre)1Kln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal neuron apoptosis
  http://purl.obolibrary.org/obo/MP_0003202

文献

http://purl.org/net/cito/citesAsAuthority

• Joerg D. Hoeck, et.al., Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun., Nature neuroscience, 2010, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/20935640