Joerg D. Hoeck, et.al., Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun., Nature neuroscience, 2010, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/20935640

Joerg D. Hoeck, et.al., Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun., Nature neuroscience, 2010, 13

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fbxw7<tm1.1Axbe>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4867641

class

http://purl.org/net/cito/citesAsAuthority

• Fbxw7<tm1.1Axbe>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4867641

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal thalamus morphology_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000832IC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeTgNescre1Kln0TgNescre1KlnFbxw7tm11Axbe
• abnormal neuron apoptosis_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Jun<tm4Wag>/Jun<+>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003202I129P2OlaHsdC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeJuntm4WagJunTgNescre1Kln0JunFbxw7tm11AxbeJuntm4WagTgNescre1Kln
• abnormal cortical intermediate zone morphology_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008457IC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeTgNescre1Kln0TgNescre1KlnFbxw7tm11Axbe
• abnormal embryonic/fetal subventricular zone morphology_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004274IC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeTgNescre1Kln0TgNescre1KlnFbxw7tm11Axbe
• abnormal tectum morphology_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Jun<tm4Wag>/Jun<+>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006104I129P2OlaHsdC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeJuntm4WagJunTgNescre1Kln0JunFbxw7tm11AxbeJuntm4WagTgNescre1Kln
• abnormal tectum morphology_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006104IC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeTgNescre1Kln0TgNescre1KlnFbxw7tm11Axbe
• abnormal cerebellum development_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000854IC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeTgNescre1Kln0TgNescre1KlnFbxw7tm11Axbe
• abnormal cortical plate morphology_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008439IC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeTgNescre1Kln0TgNescre1KlnFbxw7tm11Axbe
• decreased neuronal precursor cell number_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004981IC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeTgNescre1Kln0TgNescre1KlnFbxw7tm11Axbe
• abnormal cerebral cortex morphology_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000788IC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeTgNescre1Kln0TgNescre1KlnFbxw7tm11Axbe
• abnormal brain development_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000913IC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeTgNescre1Kln0TgNescre1KlnFbxw7tm11Axbe
• abnormal neuron differentiation_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009937IC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeTgNescre1Kln0TgNescre1KlnFbxw7tm11Axbe
• perinatal lethality_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002081IC57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeTgNescre1Kln0TgNescre1KlnFbxw7tm11Axbe
• abnormal neuron differentiation_Fbxw7<tm1.1Axbe>/Fbxw7<tm1.1Axbe>,Notch1<tm1Agt>/Notch1<+>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009937I129C57BL6SJLFbxw7tm11AxbeFbxw7tm11AxbeNotch1tm1AgtNotch1TgNescre1Kln0Fbxw7tm11AxbeNotch1tm1AgtNotch1TgNescre1Kln

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD03328
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03328
• CD03311
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03311
• CD07071
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD07071
• CD13633
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD13633
• CD03197
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03197
• CD15834
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15834
• CD12549
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12549
• CD04612
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04612
• CD13259
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD13259
• CD00494
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00494