increased neuron apoptosis_Lig4<tm1Icrf>/Lig4<tm1Icrf>

http://metadb.riken.jp/0003203EI129P2OlaHsdorI129S1Sv129X1SvJLig4tm1IcrfLig4tm1IcrfLig4tm1Icrf

increased neuron apoptosis_Lig4<tm1Icrf>/Lig4<tm1Icrf>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ligase IV, DNA, ATP-dependent
  http://metadb.riken.jp/db/mgi_rdf/MGI:1335098

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lig4<tm1Icrf>/Lig4<tm1Icrf>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lig4<tm1Icrf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129P2/OlaHsd) or (involves: 129S1/Sv * 129X1/SvJ)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased neuron apoptosis
  http://purl.obolibrary.org/obo/MP_0003203

文献

http://purl.org/net/cito/citesAsAuthority

• Y. Lee, et.al., Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm., Genes & development, 2000, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/11040211
• Kenji E. Orii, et.al., Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/16777961
• http://rdf.ncbi.nlm.nih.gov/pubmed/9889105