increased neuron apoptosis_Emx1<tm1(cre)Ito>/Emx1<+>,Tg(CAG-Mtor*)#Atai/0

http://metadb.riken.jp/0003203I129P2OlaHsdC57BL6DBA2ICREmx1tm1creItoEmx1TgCAGMtorAtai0Emx1tm1creItoEmx1TgCAGMtorAtai

increased neuron apoptosis_Emx1<tm1(cre)Ito>/Emx1<+>,Tg(CAG-Mtor*)#Atai/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion, Atsu Aiba
  http://metadb.riken.jp/db/mgi_rdf/MGI:5634711
• empty spiracles homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95387

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Emx1<tm1(cre)Ito>/Emx1<+>,Tg(CAG-Mtor*)#Atai/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Emx1<tm1(cre)Ito>|Emx1<+>|Tg(CAG-Mtor*)#Atai

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * ICR

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased neuron apoptosis
  http://purl.obolibrary.org/obo/MP_0003203

文献

http://purl.org/net/cito/citesAsAuthority

• Hidetoshi. Kassai, et.al., Selective activation of mTORC1 signaling recapitulates microcephaly, tuberous sclerosis, and neurodegenerative diseases., Cell reports, 2014, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/24857653