increased neuron apoptosis_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA*A53T)33Vle/0

http://metadb.riken.jp/0003203IC3HHeHC57BL6TgCamk2atTA1Mmay0TgtetOSNCAA53T33Vle0TgtetOSNCAA53T33VleTgCamk2atTA1Mmay

increased neuron apoptosis_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA*A53T)33Vle/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 33, Virginia M-Y Lee
  http://metadb.riken.jp/db/mgi_rdf/MGI:5289951
• transgene insertion 1, Mark Mayford
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179062

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA*A53T)33Vle/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-SNCA*A53T)33Vle|Tg(Camk2a-tTA)1Mmay

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H/HeH * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased neuron apoptosis
  http://purl.obolibrary.org/obo/MP_0003203

文献

http://purl.org/net/cito/citesAsAuthority

• Youngshin. Lim, et.al., Forebrain overexpression of alpha-synuclein leads to early postnatal hippocampal neuron loss and synaptic disruption., Experimental neurology, 2010, 221
  http://rdf.ncbi.nlm.nih.gov/pubmed/19833127