Youngshin. Lim, et.al., Forebrain overexpression of alpha-synuclein leads to early postnatal hippocampal neuron loss and synaptic disruption., Experimental neurology, 2010, 221

http://rdf.ncbi.nlm.nih.gov/pubmed/19833127

Youngshin. Lim, et.al., Forebrain overexpression of alpha-synuclein leads to early postnatal hippocampal neuron loss and synaptic disruption., Experimental neurology, 2010, 221

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-SNCA*A53T)33Vle
  http://metadb.riken.jp/db/mgi_rdf/MGI:5289968
• Tg(tetO-SNCA)7Vle
  http://metadb.riken.jp/db/mgi_rdf/MGI:5289965

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hippocampal neuron degeneration_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA*A53T)33Vle/0
  http://metadb.riken.jp/0000811IC3HHeHC57BL6TgCamk2atTA1Mmay0TgtetOSNCAA53T33Vle0TgtetOSNCAA53T33VleTgCamk2atTA1Mmay
• increased neuron apoptosis_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA*A53T)33Vle/0
  http://metadb.riken.jp/0003203IC3HHeHC57BL6TgCamk2atTA1Mmay0TgtetOSNCAA53T33Vle0TgtetOSNCAA53T33VleTgCamk2atTA1Mmay
• abnormal dentate gyrus morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA*A53T)33Vle/0
  http://metadb.riken.jp/0000812IC3HHeHC57BL6TgCamk2atTA1Mmay0TgtetOSNCAA53T33Vle0TgtetOSNCAA53T33VleTgCamk2atTA1Mmay
• gliosis_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA*A53T)33Vle/0
  http://metadb.riken.jp/0002183IC3HHeHC57BL6TgCamk2atTA1Mmay0TgtetOSNCAA53T33Vle0TgtetOSNCAA53T33VleTgCamk2atTA1Mmay
• abnormal dentate gyrus morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)7Vle/0
  http://metadb.riken.jp/0000812IC3HHeHC57BL6TgCamk2atTA1Mmay0TgtetOSNCA7Vle0TgtetOSNCA7VleTgCamk2atTA1Mmay

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-SNCA*A53T)33Vle
  http://metadb.riken.jp/db/mgi_rdf/MGI:5289968
• Tg(tetO-SNCA)7Vle
  http://metadb.riken.jp/db/mgi_rdf/MGI:5289965