increased neuron apoptosis_Tg(APP-App*R609D*K612E)7Vln/0

http://metadb.riken.jp/0003203IFVBTgAPPAppR609DK612E7Vln0TgAPPAppR609DK612E7Vln

increased neuron apoptosis_Tg(APP-App*R609D*K612E)7Vln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 7, Fred Van Leuven
  http://metadb.riken.jp/db/mgi_rdf/MGI:3720077

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(APP-App*R609D*K612E)7Vln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(APP-App*R609D*K612E)7Vln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased neuron apoptosis
  http://purl.obolibrary.org/obo/MP_0003203

文献

http://purl.org/net/cito/citesAsAuthority

• D. Moechars, et.al., Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice., The EMBO journal, 1996, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/8635459