testicular atrophy_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Ctnnb1<tm1Mmt>/Ctnnb1<+>

http://metadb.riken.jp/0003205I129S7SvEvBrd129X1SvJC57BL6Amhr2tm3creBhrAmhr2Ctnnb1tm1MmtCtnnb1Amhr2Ctnnb1Ctnnb1tm1MmtAmhr2tm3creBhr

testicular atrophy_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Ctnnb1<tm1Mmt>/Ctnnb1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• anti-Mullerian hormone type 2 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:105062
• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Amhr2<tm3(cre)Bhr>/Amhr2<+>,Ctnnb1<tm1Mmt>/Ctnnb1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Amhr2<+>|Ctnnb1<+>|Ctnnb1<tm1Mmt>|Amhr2<tm3(cre)Bhr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• testicular atrophy
  http://purl.obolibrary.org/obo/MP_0003205

文献

http://purl.org/net/cito/citesAsAuthority

• J S. Richards, et.al., Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis., Oncogene, 2012, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/21860425