decreased susceptibility to age related obesity_Gt(ROSA)26Sor<tm1(Sirt1)Ktm>/Gt(ROSA)26Sor<+>,Tg(Pomc1-cre)16Lowl/0

http://metadb.riken.jp/0003213I129C57BL6JFVBNGtROSA26Sortm1Sirt1KtmGtROSA26SorTgPomc1cre16Lowl0GtROSA26Sortm1Sirt1KtmGtROSA26SorTgPomc1cre16Lowl

decreased susceptibility to age related obesity_Gt(ROSA)26Sor<tm1(Sirt1)Ktm>/Gt(ROSA)26Sor<+>,Tg(Pomc1-cre)16Lowl/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 16, Bradford B Lowell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3640615

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Sirt1)Ktm>/Gt(ROSA)26Sor<+>,Tg(Pomc1-cre)16Lowl/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(Sirt1)Ktm>|Gt(ROSA)26Sor<+>|Tg(Pomc1-cre)16Lowl

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to age related obesity
  http://purl.obolibrary.org/obo/MP_0003213

文献

http://purl.org/net/cito/citesAsAuthority

• Tsutomu. Sasaki, et.al., Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice., Diabetologia, 2014, 57
  http://rdf.ncbi.nlm.nih.gov/pubmed/24374551