neurofibrillary tangles_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*K280,-luc)#Eman/0

http://metadb.riken.jp/0003214IC57BL6TgCamk2atTA1Mmay0TgtetOMAPTK280lucEman0TgtetOMAPTK280lucEmanTgCamk2atTA1Mmay

neurofibrillary tangles_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*K280,-luc)#Eman/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Mark Mayford
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179062
• transgene insertion, Eva-Maria Mandelkow
  http://metadb.riken.jp/db/mgi_rdf/MGI:5554184

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-MAPT*K280,-luc)#Eman/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-MAPT*K280,-luc)#Eman|Tg(Camk2a-tTA)1Mmay

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• neurofibrillary tangles
  http://purl.obolibrary.org/obo/MP_0003214

文献

http://purl.org/net/cito/citesAsAuthority

• Astrid. Sydow, et.al., Tau-induced defects in synaptic plasticity, learning, and memory are reversible in transgenic mice after switching off the toxic Tau mutant., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/21325519
• Maria-Magdalena. Mocanu, et.al., The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/18199773