increased cardiomyocyte apoptosis_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

http://metadb.riken.jp/0003222I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadNkx25tm1creRjsNkx25Gata4tm11SadNkx25Nkx25tm1creRjs

increased cardiomyocyte apoptosis_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• NK2 homeobox 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:97350
• GATA binding protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:95664

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gata4<tm1.1Sad>|Nkx2-5<+>|Nkx2-5<tm1(cre)Rjs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cardiomyocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0003222

文献

http://purl.org/net/cito/citesAsAuthority

• Toru. Oka, et.al., Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability., Circulation research, 2006, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/16514068