Toru. Oka, et.al., Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability., Circulation research, 2006, 98

http://rdf.ncbi.nlm.nih.gov/pubmed/16514068

Toru. Oka, et.al., Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability., Circulation research, 2006, 98

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6-cre)1Jmk
  http://metadb.riken.jp/db/mgi_rdf/MGI:3779100

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Myh6-cre)1Jmk
  http://metadb.riken.jp/db/mgi_rdf/MGI:3779100

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• thin ventricular wall_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0000280I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadNkx25tm1creRjsNkx25Gata4tm11SadNkx25Nkx25tm1creRjs
• dilated heart_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh6-cre)1Jmk/0
  http://metadb.riken.jp/0004937I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh6cre1Jmk0Gata4tm11SadTgMyh6cre1Jmk
• decreased cardiac muscle contractility_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh6-cre)1Jmk/0
  http://metadb.riken.jp/0005140I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh6cre1Jmk0Gata4tm11SadTgMyh6cre1Jmk
• dilated heart_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh7-cre)1Jmk/0
  http://metadb.riken.jp/0004937I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh7cre1Jmk0TgMyh7cre1JmkGata4tm11Sad
• abnormal myocardial fiber morphology_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh7-cre)1Jmk/0
  http://metadb.riken.jp/0000278I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh7cre1Jmk0TgMyh7cre1JmkGata4tm11Sad
• increased cardiomyocyte apoptosis_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0003222I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadNkx25tm1creRjsNkx25Gata4tm11SadNkx25Nkx25tm1creRjs
• pulmonary edema_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh6-cre)1Jmk/0
  http://metadb.riken.jp/0003828I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh6cre1Jmk0Gata4tm11SadTgMyh6cre1Jmk
• cardiac hypertrophy_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh7-cre)1Jmk/0
  http://metadb.riken.jp/0001625I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh7cre1Jmk0TgMyh7cre1JmkGata4tm11Sad
• abnormal heart ventricle morphology_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh7-cre)1Jmk/0
  http://metadb.riken.jp/0005294I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh7cre1Jmk0TgMyh7cre1JmkGata4tm11Sad
• premature death_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh7-cre)1Jmk/0
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh7cre1Jmk0TgMyh7cre1JmkGata4tm11Sad
• increased cardiomyocyte apoptosis_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh7-cre)1Jmk/0
  http://metadb.riken.jp/0003222I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh7cre1Jmk0TgMyh7cre1JmkGata4tm11Sad
• pulmonary edema_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh7-cre)1Jmk/0
  http://metadb.riken.jp/0003828I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh7cre1Jmk0TgMyh7cre1JmkGata4tm11Sad
• prenatal lethality, complete penetrance_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0011091I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadNkx25tm1creRjsNkx25Gata4tm11SadNkx25Nkx25tm1creRjs
• dilated heart left ventricle_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh7-cre)1Jmk/0
  http://metadb.riken.jp/0002753I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh7cre1Jmk0TgMyh7cre1JmkGata4tm11Sad
• decreased cardiac muscle contractility_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh7-cre)1Jmk/0
  http://metadb.riken.jp/0005140I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh7cre1Jmk0TgMyh7cre1JmkGata4tm11Sad
• abnormal myocardial fiber morphology_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh6-cre)1Jmk/0
  http://metadb.riken.jp/0000278I129S1Sv129X1SvJCD1Gata4tm11SadGata4tm11SadTgMyh6cre1Jmk0Gata4tm11SadTgMyh6cre1Jmk