increased cardiomyocyte apoptosis_Mdm2<tm1Glo>/Mdm2<tm2.1Glo>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0003222I129S7SvEvBrdFVBNMdm2tm1GloMdm2tm21GloTgMyh6cre2182Mds0Mdm2tm1GloMdm2tm21GloTgMyh6cre2182Mds

increased cardiomyocyte apoptosis_Mdm2<tm1Glo>/Mdm2<tm2.1Glo>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformed mouse 3T3 cell double minute 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96952
• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mdm2<tm1Glo>/Mdm2<tm2.1Glo>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mdm2<tm1Glo>|Mdm2<tm2.1Glo>|Tg(Myh6-cre)2182Mds

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cardiomyocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0003222

文献

http://purl.org/net/cito/citesAsAuthority

• Jason D. Grier, et.al., Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4., Molecular and cellular biology, 2006, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/16354690