abnormal lens epithelium morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0003237I129P2OlaHsd129S2SvPasC57BL6SJLDdb1tm1SpgDdb1tm1SpgTrp53tm1TyjTrp53tm1TyjTgNescre1Kln0TgNescre1KlnDdb1tm1SpgTrp53tm1Tyj

abnormal lens epithelium morphology_Ddb1<tm1Spg>/Ddb1<tm1Spg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• damage specific DNA binding protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202384

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ddb1<tm1Spg>/Ddb1<tm1Spg>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Kln|Ddb1<tm1Spg>|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal lens epithelium morphology
  http://purl.obolibrary.org/obo/MP_0003237

文献

http://purl.org/net/cito/citesAsAuthority

• Yong. Cang, et.al., Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells., Cell, 2006, 127
  http://rdf.ncbi.nlm.nih.gov/pubmed/17129780