loss of hippocampal neurons_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO/Prnp-TARDBP*)2Vle/0

http://metadb.riken.jp/0003240IC3HHeJC57BL6JTgCamk2atTA1Mmay0TgtetOPrnpTARDBP2Vle0TgtetOPrnpTARDBP2VleTgCamk2atTA1Mmay

loss of hippocampal neurons_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO/Prnp-TARDBP*)2Vle/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Mark Mayford
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179062
• transgene insertion 2, Virginia M Y Lee
  http://metadb.riken.jp/db/mgi_rdf/MGI:5792298

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Camk2a-tTA)1Mmay/0,Tg(tetO/Prnp-TARDBP*)2Vle/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO/Prnp-TARDBP*)2Vle|Tg(Camk2a-tTA)1Mmay

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H/HeJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• loss of hippocampal neurons
  http://purl.obolibrary.org/obo/MP_0003240

文献

http://purl.org/net/cito/citesAsAuthority

• Adam K. Walker, et.al., An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice., Human molecular genetics, 2015, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/26476406