abnormal dopaminergic neuron morphology_Tg(PDGFB-LRRK2*G2019S)32Hlw/?

http://metadb.riken.jp/0003243FVBNTgPDGFBLRRK2G2019S32HlwTgPDGFBLRRK2G2019S32HlwTgPDGFBLRRK2G2019S32Hlw

abnormal dopaminergic neuron morphology_Tg(PDGFB-LRRK2*G2019S)32Hlw/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 32, Hung-Li Wang
  http://metadb.riken.jp/db/mgi_rdf/MGI:5559902

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(PDGFB-LRRK2*G2019S)32Hlw/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(PDGFB-LRRK2*G2019S)32Hlw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB/N-Tg(PDGFB-LRRK2*G2019S)32Hlw

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal dopaminergic neuron morphology
  http://purl.obolibrary.org/obo/MP_0003243

文献

http://purl.org/net/cito/citesAsAuthority

• C-Y. Chen, et.al., (G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD., Cell death and differentiation, 2012, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/22539006