abnormal dopaminergic neuron morphology_Gt(ROSA)26Sor<tm1Lrsn>/Gt(ROSA)26Sor<+>,Mfn2<tm1.1Arte>/Mfn2<tm1.1Arte>,Slc6a3<tm1(cre)Lrsn>/Slc6a3<+>

http://metadb.riken.jp/0003243I129S1Sv129X1SvJGtROSA26Sortm1LrsnGtROSA26SorMfn2tm11ArteMfn2tm11ArteSlc6a3tm1creLrsnSlc6a3Slc6a3tm1creLrsnSlc6a3Mfn2tm11ArteGtROSA26SorGtROSA26Sortm1Lrsn

abnormal dopaminergic neuron morphology_Gt(ROSA)26Sor<tm1Lrsn>/Gt(ROSA)26Sor<+>,Mfn2<tm1.1Arte>/Mfn2<tm1.1Arte>,Slc6a3<tm1(cre)Lrsn>/Slc6a3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:94862
• mitofusin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2442230

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1Lrsn>/Gt(ROSA)26Sor<+>,Mfn2<tm1.1Arte>/Mfn2<tm1.1Arte>,Slc6a3<tm1(cre)Lrsn>/Slc6a3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Slc6a3<tm1(cre)Lrsn>|Slc6a3<+>|Mfn2<tm1.1Arte>|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1Lrsn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal dopaminergic neuron morphology
  http://purl.obolibrary.org/obo/MP_0003243

文献

http://purl.org/net/cito/citesAsAuthority

• Seungmin. Lee, et.al., Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons., Human molecular genetics, 2012, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/22914740