loss of dopaminergic neurons_Tg(PDGFB-LRRK2*R1441C)31Hlw/0

http://metadb.riken.jp/0003244FVBNTgPDGFBLRRK2R1441C31HlwTgPDGFBLRRK2R1441C31Hlw0TgPDGFBLRRK2R1441C31Hlw

loss of dopaminergic neurons_Tg(PDGFB-LRRK2*R1441C)31Hlw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 31, Hung-Li Wang
  http://metadb.riken.jp/db/mgi_rdf/MGI:5800407

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(PDGFB-LRRK2*R1441C)31Hlw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(PDGFB-LRRK2*R1441C)31Hlw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB/N-Tg(PDGFB-LRRK2*R1441C)31Hlw

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• loss of dopaminergic neurons
  http://purl.obolibrary.org/obo/MP_0003244

文献

http://purl.org/net/cito/citesAsAuthority

• Yi-Hsin. Weng, et.al., (R1441C) LRRK2 induces the degeneration of SN dopaminergic neurons and alters the expression of genes regulating neuronal survival in a transgenic mouse model., Experimental neurology, 2016, 275 Pt 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/26363496