loss of dopaminergic neurons_Ret<tm1Kln>/Ret<tm1Kln>,Slc6a3<tm1(cre)Xz>/Slc6a3<+>

http://metadb.riken.jp/0003244I129S1SvRettm1KlnRettm1KlnSlc6a3tm1creXzSlc6a3Slc6a3tm1creXzSlc6a3Rettm1Kln

loss of dopaminergic neurons_Ret<tm1Kln>/Ret<tm1Kln>,Slc6a3<tm1(cre)Xz>/Slc6a3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ret proto-oncogene
  http://metadb.riken.jp/db/mgi_rdf/MGI:97902
• solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:94862

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ret<tm1Kln>/Ret<tm1Kln>,Slc6a3<tm1(cre)Xz>/Slc6a3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Slc6a3<tm1(cre)Xz>|Slc6a3<+>|Ret<tm1Kln>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• loss of dopaminergic neurons
  http://purl.obolibrary.org/obo/MP_0003244

文献

http://purl.org/net/cito/citesAsAuthority

• Luis E. Gonzalez-Reyes, et.al., Sonic hedgehog maintains cellular and neurochemical homeostasis in the adult nigrostriatal circuit., Neuron, 2012, 75
  http://rdf.ncbi.nlm.nih.gov/pubmed/22841315