bile duct proliferation_Atp8b1<tm1Nbf>/Atp8b1<tm1Nbf>,Por<tm1Wolf>/Por<tm1Wolf>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0003255I129P2OlaHsd129S4SvJaeC57BL6DBAAtp8b1tm1NbfAtp8b1tm1NbfPortm1WolfPortm1WolfTgAlbcre21Mgn0Atp8b1tm1NbfPortm1WolfTgAlbcre21Mgn

bile duct proliferation_Atp8b1<tm1Nbf>/Atp8b1<tm1Nbf>,Por<tm1Wolf>/Por<tm1Wolf>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• ATPase, class I, type 8B, member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1859665
• P450 (cytochrome) oxidoreductase
  http://metadb.riken.jp/db/mgi_rdf/MGI:97744

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atp8b1<tm1Nbf>/Atp8b1<tm1Nbf>,Por<tm1Wolf>/Por<tm1Wolf>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Atp8b1<tm1Nbf>|Por<tm1Wolf>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• bile duct proliferation
  http://purl.obolibrary.org/obo/MP_0003255

文献

http://purl.org/net/cito/citesAsAuthority

• Cindy. Kunne, et.al., Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis., Laboratory investigation; a journal of technical methods and pathology, 2014, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/25068656