increased hepatocellular carcinoma incidence_Kras<tm4Tyj>/Kras<tm4Tyj>,Yap1<tm1.1Dupa>/Yap1<tm1.1Dupa>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0003331I129P2OlaHsd129S4SvJaeC57BL6DBAKrastm4TyjKrastm4TyjYap1tm11DupaYap1tm11DupaTgAlbcre21Mgn0Yap1tm11DupaKrastm4TyjTgAlbcre21Mgn

increased hepatocellular carcinoma incidence_Kras<tm4Tyj>/Kras<tm4Tyj>,Yap1<tm1.1Dupa>/Yap1<tm1.1Dupa>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• yes-associated protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103262

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<tm4Tyj>,Yap1<tm1.1Dupa>/Yap1<tm1.1Dupa>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Yap1<tm1.1Dupa>|Kras<tm4Tyj>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• Nailing. Zhang, et.al., The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals., Developmental cell, 2010, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/20643348