increased hepatocellular carcinoma incidence_Nf2<tm2Gth>/Nf2<tm2Gth>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0003331I129P2OlaHsdC57BL6DBANf2tm2GthNf2tm2GthTgAlbcre21Mgn0TgAlbcre21MgnNf2tm2Gth

increased hepatocellular carcinoma incidence_Nf2<tm2Gth>/Nf2<tm2Gth>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• neurofibromin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97307
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nf2<tm2Gth>/Nf2<tm2Gth>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Nf2<tm2Gth>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• Nailing. Zhang, et.al., The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals., Developmental cell, 2010, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/20643348