increased hepatocellular carcinoma incidence_Mir122<tm1Kgh>/Mir122<+>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0003331I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122TgAlbcre21Mgn0Mir122TgAlbcre21MgnMir122tm1Kgh

increased hepatocellular carcinoma incidence_Mir122<tm1Kgh>/Mir122<+>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• microRNA 122
  http://metadb.riken.jp/db/mgi_rdf/MGI:2676805

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mir122<tm1Kgh>/Mir122<+>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mir122<+>|Tg(Alb-cre)21Mgn|Mir122<tm1Kgh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• Shu-Hao. Hsu, et.al., Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver., The Journal of clinical investigation, 2012, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/22820288