Shu-Hao. Hsu, et.al., Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver., The Journal of clinical investigation, 2012, 122

http://rdf.ncbi.nlm.nih.gov/pubmed/22820288

Shu-Hao. Hsu, et.al., Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver., The Journal of clinical investigation, 2012, 122

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mir122<tm1.1Kgh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5448467
• Mir122<tm1Kgh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5448466

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating HDL cholesterol level_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0000186I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• hepatic steatosis_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002628I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased circulating alanine transaminase level_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002941I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased monocyte cell number_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000220I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• abnormal circulating enzyme level_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001570I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased tumor growth/size_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0003721I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• increased circulating interleukin-6 level_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0008596I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased circulating alanine transaminase level_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0002941I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• abnormal lipid homeostasis_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002118I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• abnormal oval cell physiology_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0010042I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• decreased tumor growth/size_Tg(tetO-MYC)36aBop/0,Tg(Cebpb-tTA)5Bjd/0
  http://metadb.riken.jp/0003447IFVBNNMRITgtetOMYC36aBop0TgCebpbtTA5Bjd0TgtetOMYC36aBopTgCebpbtTA5Bjd
• increased hepatocellular carcinoma incidence_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003331I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased neutrophil cell number_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000219I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased circulating alkaline phosphatase level_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002968I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• liver fibrosis_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0003333I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• increased tumor necrosis factor secretion_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0008560I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• bile duct proliferation_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003255I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased liver tumor incidence_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0008019I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• abnormal circulating enzyme level_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0001570I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• increased circulating interleukin-6 level_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0008596I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• decreased circulating cholesterol level_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0005179I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• liver inflammation_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001860I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased bile salt level_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0004789I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased bile salt level_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0004789I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• decreased liver glycogen level_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0010398I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased hepatocellular carcinoma incidence_Tg(tetO-MYC)36aBop/0,Tg(Cebpb-tTA)5Bjd/0
  http://metadb.riken.jp/0003331IFVBNNMRITgtetOMYC36aBop0TgCebpbtTA5Bjd0TgtetOMYC36aBopTgCebpbtTA5Bjd
• increased hepatocellular carcinoma incidence_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0003331I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• increased hepatocellular carcinoma incidence_Mir122<tm1.1Kgh>/Mir122<+>
  http://metadb.riken.jp/0003331I129S1Sv129X1SvJMir122tm11KghMir122Mir122tm11KghMir122
• increased hepatocellular carcinoma incidence_Mir122<tm1Kgh>/Mir122<+>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003331I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122TgAlbcre21Mgn0Mir122TgAlbcre21MgnMir122tm1Kgh
• hepatic steatosis_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0002628I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• increased liver triglyceride level_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0009355I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• increased interleukin-6 secretion_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0008705I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• decreased circulating cholesterol level_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005179I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• decreased circulating LDL cholesterol level_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000183I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased circulating alkaline phosphatase level_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0002968I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• liver inflammation_Mir122<tm1.1Kgh>/Mir122<tm1.1Kgh>
  http://metadb.riken.jp/0001860I129S1Sv129X1SvJMir122tm11KghMir122tm11KghMir122tm11Kgh
• liver fibrosis_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0003333I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• decreased circulating HDL cholesterol level_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000186I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• abnormal liver physiology_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0000609I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn
• increased liver triglyceride level_Mir122<tm1Kgh>/Mir122<tm1Kgh>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0009355I129S1Sv129X1SvJC57BL6DBAMir122tm1KghMir122tm1KghTgAlbcre21Mgn0Mir122tm1KghTgAlbcre21Mgn

class

http://purl.org/net/cito/citesAsAuthority

• Mir122<tm1.1Kgh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5448467
• Mir122<tm1Kgh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5448466