increased hepatocellular carcinoma incidence_Tg(tetO-MYC)36aBop/0,Tg(Cebpb-tTA)5Bjd/0

http://metadb.riken.jp/0003331IFVBNNMRITgtetOMYC36aBop0TgCebpbtTA5Bjd0TgtetOMYC36aBopTgCebpbtTA5Bjd

increased hepatocellular carcinoma incidence_Tg(tetO-MYC)36aBop/0,Tg(Cebpb-tTA)5Bjd/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 36a, J Michael Bishop
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459071
• transgene insertion 5, Hermann Bujard
  http://metadb.riken.jp/db/mgi_rdf/MGI:3056822

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(tetO-MYC)36aBop/0,Tg(Cebpb-tTA)5Bjd/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-MYC)36aBop|Tg(Cebpb-tTA)5Bjd

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB/N * NMRI

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased hepatocellular carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0003331

文献

http://purl.org/net/cito/citesAsAuthority

• Shu-Hao. Hsu, et.al., Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver., The Journal of clinical investigation, 2012, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/22820288
• Catherine M. Shachaf, et.al., MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer., Nature, 2004, 431
  http://rdf.ncbi.nlm.nih.gov/pubmed/15475948
• Louis A. Saddic, et.al., Functional interactions between retinoblastoma and c-MYC in a mouse model of hepatocellular carcinoma., PloS one, 2011, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/21573126