liver fibrosis_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0

http://metadb.riken.jp/0003333I129P2OlaHsdC57BL6FVBNCasp8tm1ClieCasp8tm1ClieIkbkgtm11ChtrIkbkgtm11ChtrTgAlb1cre7Gsc0Ikbkgtm11ChtrCasp8tm1ClieTgAlb1cre7Gsc

liver fibrosis_Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• inhibitor of kappaB kinase gamma
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338074
• transgene insertion 7, Gunther Schutz
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177601
• caspase 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261423

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Casp8<tm1Clie>/Casp8<tm1Clie>,Ikbkg<tm1.1Chtr>/Ikbkg<tm1.1Chtr>,Tg(Alb1-cre)7Gsc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ikbkg<tm1.1Chtr>|Casp8<tm1Clie>|Tg(Alb1-cre)7Gsc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• liver fibrosis
  http://purl.obolibrary.org/obo/MP_0003333

文献

http://purl.org/net/cito/citesAsAuthority

• Christian. Liedtke, et.al., Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury., Gastroenterology, 2011, 141
  http://rdf.ncbi.nlm.nih.gov/pubmed/21878202